HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 56297

HXB2 Location  Gag(22-30)   Gag Epitope Map
View variants at this location
Epitope RPGGKKKKYK   Epitope Alignment
RPGGKKKKYr   susceptible form
Species (MHC/HLA human(B7)

Variant Details

Showing 1 of 3 variants.

Variant ID.  158
Epitope Seq.  RPGGKKKKYK
Variant Seq.  RPGGKKKKYr
Mutations K/R
Epitope Location K10R
HXB2 Location K31R
Mutation Type SF: susceptible form
Method Flow cytometric T-cell cytokine assay
Note RPGGKKKKYK was recognized by 3 patients. One patient had variants RPGGrKKrYK, RPGGKKKrYK, RPGGKKKKYr which were well recognized. Variant RPGGKKKKYr was also present and recognized in other 2 patients


Daucher2008 Marybeth Daucher, David A. Price, Jason M. Brenchley, Laurie Lamoreaux, Julia A. Metcalf, Catherine Rehm, Elizabeth Nies-Kraske, Elizabeth Urban, Christian Yoder, Diane Rock, Julie Gumkowski, Michael R. Betts, Mark R. Dybul, and Daniel C. Douek. Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells. J. Virol., 82(8):4102-4114, Apr 2008. PubMed ID: 18234797. Show all entries for this paper.

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