HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Gag(20-29)|| Gag Epitope Map
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Showing 1 of 2 variants.
|Mutation Type||DR: diminished response|
|Method||CD8 T-cell Elispot - IFNy, Sequence|
|Note||This variant from the HXB2 sequence was present in the restricting HLA-A30 allele carrying mother, M-1002, as well as her HLA-A30-carrying infant, P-1031. Decreased recognition of the variant was seen relative to index epitope in the mother. The variant was detected at decreasing frequencies by 11 months of age in infant P-1031, but recognition was equivalent to index epitope recognition in the infant.|
Sanchez-Merino2005 Victor Sanchez-Merino, Siwei Nie, and Katherine Luzuriaga. HIV-1-Specific CD8+ T Cell Responses and Viral Evolution in Women and Infants. J. Immunol., 175(10):6976-6986, 15 Nov 2005. PubMed ID: 16272358. Show all entries for this paper.