HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 53838

HXB2 Location  Gag(18-26)   Gag Epitope Map
View variants at this location
Epitope KIRLRPGGK   Epitope Alignment
Variants
KIRLRPGGr   literature escape; observed variant
Epitope Name KR9
Species (MHC/HLA human(A*03)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1570
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIRLRPGGr
Mutations K/R
Epitope Location K9R
HXB2 Location K26R
Mutation Type LE: literature escape
OV: observed variant
Method Sequence
Note This variant from the HXB2 sequence was present in the restricting HLA-A3 allele carrying mother, M-1001, as well as her HLA-A*31-carrying infant, P-1024. Infant P-1024 had lost this variant by 15 months of age.

References

Sanchez-Merino2005 Victor Sanchez-Merino, Siwei Nie, and Katherine Luzuriaga. HIV-1-Specific CD8+ T Cell Responses and Viral Evolution in Women and Infants. J. Immunol., 175(10):6976-6986, 15 Nov 2005. PubMed ID: 16272358. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health