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Displaying record number 56297

HXB2 Location Gag(22-30) Gag Epitope Map
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Epitope

RPGGKKKKYK

Epitope Alignment

Variants

RPGGrKKrYK susceptible form

Species (MHC/HLA) human(B7)

Variant Details

Showing 1 of 3 variants.

Variant ID.	`156`
Epitope Seq.	`RPGGKKKKYK`
Variant Seq.	`RPGGrKKrYK`
Mutations	K/R K/R
Epitope Location	K5R K8R
HXB2 Location	K26R K29R
Mutation Type	SF: susceptible form
Method	Flow cytometric T-cell cytokine assay
Note	RPGGKKKKYK was recognized by 3 patients. One patient had variants RPGGrKKrYK, RPGGKKKrYK, RPGGKKKKYr which were well recognized. Variant RPGGKKKKYr was also present and recognized in other 2 patients

References

Daucher2008 Marybeth Daucher, David A. Price, Jason M. Brenchley, Laurie Lamoreaux, Julia A. Metcalf, Catherine Rehm, Elizabeth Nies-Kraske, Elizabeth Urban, Christian Yoder, Diane Rock, Julie Gumkowski, Michael R. Betts, Mark R. Dybul, and Daniel C. Douek. Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells. J. Virol., 82(8):4102-4114, Apr 2008. PubMed ID: 18234797. Show all entries for this paper.