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Displaying record number 196

HXB2 Location  Gag(183-191)   Gag Epitope Map
View variants at this location
Epitope DLNTMLNTV   Epitope Alignment
Variants
DLNnMLNiV   susceptible form
Species (MHC/HLA human(B*14:02, Cw8)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1543
Epitope Seq.  DLNTMLNTV
Variant Seq.  DLNnMLNiV
Mutations T/N T/I
Epitope Location T4N T8I
HXB2 Location T186N T190I
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype A
Method Chromium-release assay
Note One HEPS Kenyan subject cross-reacted to this B clade epitope but elicited a stronger reaction to the A clade form, DLNnMLNiV.

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


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