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Displaying record number 101

HXB2 Location Gag(77-85) Gag Epitope Map
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Epitope

SLYNTVATL

Epitope Alignment

Variants

SLfNTVATL susceptible form

Epitope Name SL9

Species (MHC/HLA) human(A*02:02, A2)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1542`
Epitope Seq.	`SLYNTVATL`
Variant Seq.	`SLfNTVATL`
Mutations	Y/F
Epitope Location	Y3F
HXB2 Location	Y79F
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	A
Method	Chromium-release assay
Note	Two HEPS Kenyan subjects cross-reacted to this B clade epitope and one of them elicited a stronger reaction to the A clade form, SLfNTVATL

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.