Search the Epitope Variant and Escape Mutation Database

Help

Found 1 matching record:

Displaying record number 56296

HXB2 Location Gag(20-28) Gag Epitope Map
View variants at this location

Epitope

RLRPGGKKK

Epitope Alignment

Variants

RLRPGGrKr susceptible form

Epitope Name RK9

Species (MHC/HLA) human(A3, B7)

Variant Details

Showing 1 of 2 variants.

Variant ID.	`154`
Epitope Seq.	`RLRPGGKKK`
Variant Seq.	`RLRPGGrKr`
Mutations	K/R K/R
Epitope Location	K7R K9R
HXB2 Location	K26R K28R
Mutation Type	SF: susceptible form
Method	Flow cytometric T-cell cytokine assay
Note	RLRPGGKKK was recognized by 3 patients. One patient had variants RLRPGGrKr and RLRPGGKKr, which were well recognized within longer peptides.

References

Daucher2008 Marybeth Daucher, David A. Price, Jason M. Brenchley, Laurie Lamoreaux, Julia A. Metcalf, Catherine Rehm, Elizabeth Nies-Kraske, Elizabeth Urban, Christian Yoder, Diane Rock, Julie Gumkowski, Michael R. Betts, Mark R. Dybul, and Daniel C. Douek. Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells. J. Virol., 82(8):4102-4114, Apr 2008. PubMed ID: 18234797. Show all entries for this paper.