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Found 1 matching record:

Displaying record number 55770

HXB2 Location  Gag(18-26)   Gag Epitope Map
View variants at this location
Epitope KIRLRPGGK   Epitope Alignment
Variants
KIRLRPGGr   susceptible form
Epitope Name KK9
Species (MHC/HLA human(A3)

Variant Details

Showing all: 1 variant(s).


Variant ID.  153
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIRLRPGGr
Mutations K/R
Epitope Location K9R
HXB2 Location K26R
Mutation Type SF: susceptible form
Method Flow cytometric T-cell cytokine assay
Note KIRLRPGGK was recognized by 3 patients. The autologous sequence in one patient was KIRLRPGGr which induced high frequency response.

References

Daucher2008 Marybeth Daucher, David A. Price, Jason M. Brenchley, Laurie Lamoreaux, Julia A. Metcalf, Catherine Rehm, Elizabeth Nies-Kraske, Elizabeth Urban, Christian Yoder, Diane Rock, Julie Gumkowski, Michael R. Betts, Mark R. Dybul, and Daniel C. Douek. Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells. J. Virol., 82(8):4102-4114, Apr 2008. PubMed ID: 18234797. Show all entries for this paper.


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