HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 55054

HXB2 Location  Gag(180-188)   Gag Epitope Map
View variants at this location
Epitope TPQDLNMML   Epitope Alignment
TPQDLNtML   subtype-specific non-susceptible form; subtype-specific susceptible form
Species (MHC/HLA human(B*42:02)

Variant Details

Showing all: 1 variant(s).

Variant ID.  144
Epitope Seq.  TPQDLNMML
Variant Seq.  TPQDLNtML
Mutations M/T
Epitope Location M7T
HXB2 Location M186T
Mutation Type SNSF: subtype-specific non-susceptible form
SSF: subtype-specific susceptible form
Note TPQDLNMML within peptide EGATPQDLNMMLNIV from A consensus and A isolate was recognized by 4 HLA B*4202 carriers from subtype A Kenyan cohort. The variant TPQDLNtML within peptide EGATPQDLNtMLNtV from C and D isolates was recognized by only 1 out 4 subjects that recognized TPQDLNMML.


Currier2006 Jeffrey R. Currier, Unchalee Visawapoka, Sodsai Tovanabutra, Carl J. Mason, Deborah L. Birx, Francine E. McCutchan, and Josephine H. Cox. CTL Epitope Distribution Patterns in the Gag and Nef Proteins of HIV-1 from Subtype A Infected Subjects in Kenya: Use of Multiple Peptide Sets Increases the Detectable Breadth of the CTL Response. BMC Immunol, 7:8, 2006. PubMed ID: 16620386. Show all entries for this paper.

Questions or comments? Contact us at
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health