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Found 1 matching record:

Displaying record number 53832

HXB2 Location  Gag(147-155)   Gag Epitope Map
View variants at this location
Epitope ISPRTLNAW   Epitope Alignment
Variants
mSPRTLNAW   escape documented in this paper
Species (MHC/HLA human(B57)

Variant Details

Showing 1 of 3 variants.


Variant ID.  1413
Epitope Seq.  ISPRTLNAW
Variant Seq.  mSPRTLNAW
Mutations I/M
Epitope Location I1M
HXB2 Location I147M
Mutation Type E: escape documented in this paper
Method CD8 T-cell Elispot - IFNy, Sequence
Note This is de novo variant seen in infant by week 33 of age. The index peptide was recognized, but not the variant.

References

Pillay2005 Thillagavathie Pillay, Hua-Tang Zhang, Jan W. Drijfhout, Nicola Robinson, Helen Brown, Munira Khan, Jagadesa Moodley, Miriam Adhikari, Katja Pfafferott, Margaret E. Feeney, Anne St. John, Edward C. Holmes, Hoosen M. Coovadia, Paul Klenerman, Philip J. R. Goulder, and Rodney E. Phillips. Unique Acquisition of Cytotoxic T-Lymphocyte Escape Mutants in Infant Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(18):12100-12105, Sep 2005. PubMed ID: 16140787. Show all entries for this paper.


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