Found 1 matching record:
HXB2 Location | Gag(147-155) | Gag Epitope Map
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Epitope |
ISPRTLNAW
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Epitope Alignment | ||||
Variants |
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Species (MHC/HLA) | human(B57) |
Showing 1 of 3 variants.
Variant ID. | 1413 |
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Epitope Seq. | ISPRTLNAW |
Variant Seq. | mSPRTLNAW |
Mutations | I/M |
Epitope Location | I1M |
HXB2 Location | I147M |
Mutation Type | E: escape documented in this paper |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This is de novo variant seen in infant by week 33 of age. The index peptide was recognized, but not the variant. |
Pillay2005 Thillagavathie Pillay, Hua-Tang Zhang, Jan W. Drijfhout, Nicola Robinson, Helen Brown, Munira Khan, Jagadesa Moodley, Miriam Adhikari, Katja Pfafferott, Margaret E. Feeney, Anne St. John, Edward C. Holmes, Hoosen M. Coovadia, Paul Klenerman, Philip J. R. Goulder, and Rodney E. Phillips. Unique Acquisition of Cytotoxic T-Lymphocyte Escape Mutants in Infant Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(18):12100-12105, Sep 2005. PubMed ID: 16140787. Show all entries for this paper.
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