HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 53421

HXB2 Location  Gag(210-218)   Gag Epitope Map
View variants at this location
Epitope AEWDRLHPV   Epitope Alignment
AdWDRvHPV   observed variant
Epitope Name AEW
Species (MHC/HLA human(A2)

Variant Details

Showing 1 of 3 variants.

Variant ID.  1352
Epitope Seq.  AEWDRLHPV
Variant Seq.  AdWDRvHPV
Mutations E/D L/V
Epitope Location E2D L6V
HXB2 Location E211D L215V
Mutation Type OV: observed variant
Method CD8 T-cell Elispot - IFNy, Sequence, Tetramer binding
Note Only 1/18 viral clones contained this variant sequence at the first time point tested after infection.


Oxenius2004 Annette Oxenius, David A. Price, Alexandra Trkola, Charles Edwards, Emma Gostick, Hua-Tang Zhang, Philippa J. Easterbrook, Tin Tun, Andrew Johnson, Anele Waters, Edward C. Holmes, and Rodney E. Phillips. Loss of Viral Control in Early HIV-1 Infection Is Temporally Associated with Sequential Escape from CD8+ T Cell Responses and Decrease in HIV-1-Specific CD4+ and CD8+ T Cell Frequencies. J. Infect. Dis., 190(4):713-721, 15 Aug 2004. PubMed ID: 15272399. Show all entries for this paper.

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