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Found 1 matching record:

Displaying record number 53822

HXB2 Location  Gag(93-101)   Gag Epitope Map
View variants at this location
Epitope EVKDTKEAL   Epitope Alignment
Variants
dVKgTKEAL   escape documented in this paper
Species (MHC/HLA human(B*08:01)

Variant Details

Showing 1 of 2 variants.


Variant ID.  1308
Epitope Seq.  EVKDTKEAL
Variant Seq.  dVKgTKEAL
Mutations E/D D/G
Epitope Location E1D D4G
HXB2 Location E93D D96G
Mutation Type E: escape documented in this paper
Method CD8 T-cell Elispot - IFNy, Sequence
Note This variant was found in Donor2 but not transmitted to Recipient2. The variant was not recognized by CTL. Both donor and recipient carried the restricting HLA-B*0801 allele

References

Milicic2005 Anita Milicic, Charles T. T. Edwards, Stéphane Hué, Julie Fox, Helen Brown, Tilly Pillay, Jan W. Drijfhout, Jonathan N. Weber, Edward C. Holmes, Sarah J. Fidler, Hua-Tang Zhang, and Rodney E. Phillips. Sexual Transmission of Single Human Immunodeficiency Virus Type 1 Virions Encoding Highly Polymorphic Multisite Cytotoxic T-Lymphocyte Escape Variants. J. Virol., 79(22):13953-13962, Nov 2005. PubMed ID: 16254331. Show all entries for this paper.


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