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Search the Epitope Variant and Escape Mutation Database


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Displaying record number 53822

HXB2 Location  Gag(93-101)   Gag Epitope Map
View variants at this location
Epitope EVKDTKEAL   Epitope Alignment
dVKgTKEAL   escape documented in this paper
Species (MHC/HLA human(B*08:01)

Variant Details

Showing 1 of 2 variants.

Variant ID.  1308
Epitope Seq.  EVKDTKEAL
Variant Seq.  dVKgTKEAL
Mutations E/D D/G
Epitope Location E1D D4G
HXB2 Location E93D D96G
Mutation Type E: escape documented in this paper
Method CD8 T-cell Elispot - IFNy, Sequence
Note This variant was found in Donor2 but not transmitted to Recipient2. The variant was not recognized by CTL. Both donor and recipient carried the restricting HLA-B*0801 allele


Milicic2005 Anita Milicic, Charles T. T. Edwards, Stéphane Hué, Julie Fox, Helen Brown, Tilly Pillay, Jan W. Drijfhout, Jonathan N. Weber, Edward C. Holmes, Sarah J. Fidler, Hua-Tang Zhang, and Rodney E. Phillips. Sexual Transmission of Single Human Immunodeficiency Virus Type 1 Virions Encoding Highly Polymorphic Multisite Cytotoxic T-Lymphocyte Escape Variants. J. Virol., 79(22):13953-13962, Nov 2005. PubMed ID: 16254331. Show all entries for this paper.

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