HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Gag(24-31)|| Gag Epitope Map
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Showing 1 of 2 variants.
|Epitope Location||K5Q K7R|
|HXB2 Location||K28Q K30R|
|Mutation Type||DHB: diminished HLA binding or increased off-rate
E: escape documented in this paper
|Method||CD8 T-cell Elispot - IFNy, HLA binding, Sequence|
|Note||This anchor residue variant was seen in Donor2 and Recipient2, both of whom carried the restricting HLA-B*0801 allele. It was not recognized and binding to HLA was greatly reduced.|
Milicic2005 Anita Milicic, Charles T. T. Edwards, Stéphane Hué, Julie Fox, Helen Brown, Tilly Pillay, Jan W. Drijfhout, Jonathan N. Weber, Edward C. Holmes, Sarah J. Fidler, Hua-Tang Zhang, and Rodney E. Phillips. Sexual Transmission of Single Human Immunodeficiency Virus Type 1 Virions Encoding Highly Polymorphic Multisite Cytotoxic T-Lymphocyte Escape Variants. J. Virol., 79(22):13953-13962, Nov 2005. PubMed ID: 16254331. Show all entries for this paper.