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Found 1 matching record:

Displaying record number 53819

HXB2 Location  Gag(24-31)   Gag Epitope Map
View variants at this location
Epitope GGKKKYKL   Epitope Alignment
Variants
GGrKKYKL   escape documented in this paper
Epitope Name GL8
Species (MHC/HLA human(B*08:01)

Variant Details

Showing 1 of 2 variants.


Variant ID.  1304
Epitope Seq.  GGKKKYKL
Variant Seq.  GGrKKYKL
Mutations K/R
Epitope Location K3R
HXB2 Location K26R
Mutation Type E: escape documented in this paper
Method CD8 T-cell Elispot - IFNy, Sequence
Note This variant was seen in Donor1 and Recipient1, where only the donor carried the restricting HLA-B*0801 allele. It was not recognized by either subject.

References

Milicic2005 Anita Milicic, Charles T. T. Edwards, Stéphane Hué, Julie Fox, Helen Brown, Tilly Pillay, Jan W. Drijfhout, Jonathan N. Weber, Edward C. Holmes, Sarah J. Fidler, Hua-Tang Zhang, and Rodney E. Phillips. Sexual Transmission of Single Human Immunodeficiency Virus Type 1 Virions Encoding Highly Polymorphic Multisite Cytotoxic T-Lymphocyte Escape Variants. J. Virol., 79(22):13953-13962, Nov 2005. PubMed ID: 16254331. Show all entries for this paper.


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