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Found 1 matching record:

Displaying record number 53817

HXB2 Location  Gag(20-28)   Gag Epitope Map
View variants at this location
Epitope RLRPGGKKK   Epitope Alignment
Variants
RLRPGGrKK   observed variant
Species (MHC/HLA human(A*03:01)

Variant Details

Showing 1 of 3 variants.


Variant ID.  1301
Epitope Seq.  RLRPGGKKK
Variant Seq.  RLRPGGrKK
Mutations K/R
Epitope Location K7R
HXB2 Location K26R
Mutation Type OV: observed variant
Method CD8 T-cell Elispot - IFNy, HLA binding, Sequence
Note This K26R variant was found in both Donor1 and Recipient1. The restricting HLA-A*0301 was only carried in the Donor.

References

Milicic2005 Anita Milicic, Charles T. T. Edwards, Stéphane Hué, Julie Fox, Helen Brown, Tilly Pillay, Jan W. Drijfhout, Jonathan N. Weber, Edward C. Holmes, Sarah J. Fidler, Hua-Tang Zhang, and Rodney E. Phillips. Sexual Transmission of Single Human Immunodeficiency Virus Type 1 Virions Encoding Highly Polymorphic Multisite Cytotoxic T-Lymphocyte Escape Variants. J. Virol., 79(22):13953-13962, Nov 2005. PubMed ID: 16254331. Show all entries for this paper.


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