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Displaying record number 74

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLYNTiATL   subtype-specific susceptible form
Epitope Name SL9
Species (MHC/HLA human(A*02:01)

Variant Details

Showing 1 of 3 variants.


Variant ID.  1113
Epitope Seq.  SLYNTVATL
Variant Seq.  SLYNTiATL
Mutations V/I
Epitope Location V6I
HXB2 Location V82I
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype D
Method Chromium-release assay
Note Recombinant vaccinia virus containing this Clade D circulating Ugandan variant was well recognized by a CTL clone from a Clade B-infected patient. A natural variant with the same substitution was found in the same Clade B carrying patient.

References

McAdam1998 S. McAdam, P. Kaleebu, P. Krausa, P. Goulder, N. French, B. Collin, T. Blanchard, J. Whitworth, A. McMichael, and F. Gotch. Cross-Clade Recognition of p55 by Cytotoxic T Lymphocytes in HIV-1 Infection. AIDS, 12:571-579, 1998. PubMed ID: 9583596. Show all entries for this paper.


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