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Found 1 matching record:

Displaying record number 54495

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
aLYNTaAaL   non-susceptible form
Epitope Name SL9
Species (MHC/HLA human(A2)

Variant Details

Showing 1 of 22 variants.


Variant ID.  1067
Epitope Seq.  SLYNTVATL
Variant Seq.  aLYNTaAaL
Mutations S/A V/A T/A
Epitope Location S1A V6A T8A
HXB2 Location S77A V82A T84A
Mutation Type NSF: non-susceptible form
Method Chromium-release assay, Sequence
Note This synthetic variant when tested in the presence of D3 TCR, Gag-specific CTL elicited no response.

References

Martinez-Hackert2006 Erik Martinez-Hackert, Nadia Anikeeva, Spyros A. Kalams, Bruce D. Walker, Wayne A. Hendrickson, and Yuri Sykulev. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J. Biol. Chem., 281(29):20205-20212, 21 Jul 2006. PubMed ID: 16702212. Show all entries for this paper.


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