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Found 1 matching record:

Displaying record number 54495

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
aLYNTVATL   susceptible form
Epitope Name SL9
Species (MHC/HLA human(A2)

Variant Details

Showing 1 of 22 variants.


Variant ID.  1062
Epitope Seq.  SLYNTVATL
Variant Seq.  aLYNTVATL
Mutations S/A
Epitope Location S1A
HXB2 Location S77A
Mutation Type SF: susceptible form
Method Chromium-release assay, Sequence
Note This synthetic variant when tested in the presence of D3 TCR, Gag-specific CTL was susceptible, indistinguishable from the wild type SL9.

References

Martinez-Hackert2006 Erik Martinez-Hackert, Nadia Anikeeva, Spyros A. Kalams, Bruce D. Walker, Wayne A. Hendrickson, and Yuri Sykulev. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J. Biol. Chem., 281(29):20205-20212, 21 Jul 2006. PubMed ID: 16702212. Show all entries for this paper.


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