HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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| Epitope |
SLYNTVATL
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | SL9 | |||||
| Species (MHC/HLA) | human(A2) | |||||
Showing 1 of 22 variants.
| Variant ID. | 1055 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLfNTVATL |
| Mutations | Y/F |
| Epitope Location | Y3F |
| HXB2 Location | Y79F |
| Mutation Type | SF: susceptible form |
| Method | Chromium-release assay, Sequence |
| Note | This natural variant when tested in the presence of D3 TCR, Gag-specific CTL was susceptible and only very slightly less active than wild type SL9. |
Martinez-Hackert2006 Erik Martinez-Hackert, Nadia Anikeeva, Spyros A. Kalams, Bruce D. Walker, Wayne A. Hendrickson, and Yuri Sykulev. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J. Biol. Chem., 281(29):20205-20212, 21 Jul 2006. PubMed ID: 16702212. Show all entries for this paper.