HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(147-155) | Gag Epitope Map
View variants at this location |
||||
|---|---|---|---|---|---|---|
| Epitope |
ISPRTLNAW
|
Epitope Alignment | ||||
| Variants |
|
|||||
| Epitope Name | IW9 | |||||
| Species (MHC/HLA) | human(B57) | |||||
Showing all: 1 variant(s).
| Variant ID. | 1021 |
|---|---|
| Epitope Seq. | ISPRTLNAW |
| Variant Seq. | lSPRTLNAW |
| Mutations | I/L |
| Epitope Location | I1L |
| HXB2 Location | I147L |
| Mutation Type | SSF: subtype-specific susceptible form |
| Epitope Subtype | B |
| Variant Subtype | A |
| Method | CD8 T-cell Elispot - IFNy |
| Note | Cross-recognition of this variant is seen with both C- and A-clades. Anchor residues are at positions 2 and 9; while the A-clade variant contains a change at position 1 to lSPRTLNAW. |
Malhotra2007 Uma Malhotra, Jessica Nolin, James I. Mullins, and M. Juliana McElrath. Comprehensive Epitope Analysis of Cross-Clade Gag-Specific T-Cell Responses in Individuals with Early HIV-1 Infection in the US Epidemic. Vaccine, 25(2):381-390, 4 Jan 2007. PubMed ID: 17112643. Show all entries for this paper.