HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Gag(20-28)|| Gag Epitope Map
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Showing all: 1 variant(s).
|Mutation Type||DR: diminished response|
|Method||CD8 T-cell Elispot - IFNy|
|Note||Cross-recognition of the variant is seen with both C- and A-clades. The C-clade variant contains a change at position 9 to RLRPGGKKh. Typically, magnitude and avidity of binding for T-cell responses were much lower to the C-clade variant.|
Malhotra2007 Uma Malhotra, Jessica Nolin, James I. Mullins, and M. Juliana McElrath. Comprehensive Epitope Analysis of Cross-Clade Gag-Specific T-Cell Responses in Individuals with Early HIV-1 Infection in the US Epidemic. Vaccine, 25(2):381-390, 4 Jan 2007. PubMed ID: 17112643. Show all entries for this paper.