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Found 3 matching records:

Displaying record number 60669

HXB2 Location Gag(28-36) Gag Epitope Map
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KYRLKHIVW

`qYkLKHIVW`		observed variant; susceptible form
`rYrLKHlVW`		observed variant; susceptible form

Species (MHC/HLA) human(A*24:02)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`3551`
Epitope Seq.	`KYRLKHIVW`
Variant Seq.	`qYkLKHIVW`
Mutations	K/Q R/K
Epitope Location	K1Q R3K
HXB2 Location	K28Q R30K
Mutation Type	OV: observed variant SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Other
Note	Autologous variant Gag qYkLKHIVW of subject S3 also elicits a greater CTL response from DC-primed naive T cells than DC-stimulated memory T cells.

Variant ID.	`3552`
Epitope Seq.	`KYRLKHIVW`
Variant Seq.	`rYrLKHlVW`
Mutations	K/R I/L
Epitope Location	K1R I7L
HXB2 Location	K28R I34L
Mutation Type	OV: observed variant SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Other
Note	Contrary to most cases, autologous variant Gag rYRLKHlVW of subject S4 elicits a smaller CTL response from DC-primed naive T cells than DC-stimulated memory T cells.

References

Smith2016 Kellie N. Smith, Robbie B. Mailliard, Paolo A. Piazza, Will Fischer, Bette T. Korber, Ronald J. Fecek, Deena Ratner, Phalguni Gupta, James I. Mullins, and Charles R. Rinaldo. Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells. MBio, 7(3), 31 May 2016. PubMed ID: 27247230. Show all entries for this paper.

Displaying record number 60671

HXB2 Location Gag(28-36) Gag Epitope Map
View variants at this location

Epitope

QYKLKHIVW

Epitope Alignment

Variants

`kYrLKHIVW`		observed variant; susceptible form
`rYrLKHlVW`		observed variant; susceptible form

Species (MHC/HLA) human(A*24:02)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`3553`
Epitope Seq.	`QYKLKHIVW`
Variant Seq.	`kYrLKHIVW`
Mutations	Q/K K/R
Epitope Location	Q1K K3R
HXB2 Location	Q28K K30R
Mutation Type	OV: observed variant SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Other
Note	Autologous variant Gag kYrLKHIVW of subject S2 also elicits a greater CTL response from DC-primed naive T cells than DC-stimulated memory T cells.

Variant ID.	`3554`
Epitope Seq.	`QYKLKHIVW`
Variant Seq.	`rYrLKHlVW`
Mutations	Q/R K/R I/L
Epitope Location	Q1R K3R I7L
HXB2 Location	Q28R K30R I34L
Mutation Type	OV: observed variant SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Other
Note	Contrary to most cases, autologous variant Gag rYrLKHlVW of subject S4 elicits a smaller CTL response from DC-primed naive T cells than DC-stimulated memory T cells.

References

Displaying record number 60672

HXB2 Location Gag(28-36) Gag Epitope Map
View variants at this location

Epitope

RYRLKHLVW

Epitope Alignment

Variants

`kYRLKHiVW`		observed variant; susceptible form
`qYkLKHiVW`		observed variant; susceptible form

Species (MHC/HLA) human(A*24:02)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`3555`
Epitope Seq.	`RYRLKHLVW`
Variant Seq.	`kYRLKHiVW`
Mutations	R/K L/I
Epitope Location	R1K L7I
HXB2 Location	R28K L34I
Mutation Type	OV: observed variant SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Other
Note	Autologous variant Gag kYRLKHiVW of subject S2 also elicits a greater CTL response from DC-primed naive T cells than DC-stimulated memory T cells.

Variant ID.	`3556`
Epitope Seq.	`RYRLKHLVW`
Variant Seq.	`qYkLKHiVW`
Mutations	R/Q R/K L/I
Epitope Location	R1Q R3K L7I
HXB2 Location	R28Q R30K L34I
Mutation Type	OV: observed variant SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Other
Note	Autologous variant Gag qYkLKHiVW of subject S3 also elicits a greater CTL response from DC-primed naive T cells than DC-stimulated memory T cells.