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Found 6 matching records:

Displaying record number 61459

HXB2 Location  Gag(73-90)   Gag Epitope Map
View variants at this location
Epitope EELKSLFNTIAVLWCVHQ   Epitope Alignment
Variants
EELKSLFNTvAVLWCVHk   observed variant
EELKSLFNTvAVLWCVHQ   observed variant
EELKSLFNTvAVLcCVHQ   observed variant
EELKpLFNTvAVLcCVHQ   observed variant
Epitope Name OLP-10
Species (MHC/HLA human

Variant Details

Showing all: 4 variant(s).


Variant ID.  3877
Epitope Seq.  EELKSLFNTIAVLWCVHQ
Variant Seq.  EELKSLFNTvAVLWCVHk
Mutations I/V Q/K
Epitope Location I10V Q18K
HXB2 Location I82V Q90K
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other
Note Subject 3 had I82V, Q90K, variations in 1/15 sequences at 3 months, within and downstream of the putative epitope LFNTVAVL.


Variant ID.  3878
Epitope Seq.  EELKSLFNTIAVLWCVHQ
Variant Seq.  EELKSLFNTvAVLWCVHQ
Mutations I/V
Epitope Location I10V
HXB2 Location I82V
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other
Note Subject 3 had I82V variation in 14/15 sequences at 3 months, within the putative epitope LFNTVAVL.


Variant ID.  3879
Epitope Seq.  EELKSLFNTIAVLWCVHQ
Variant Seq.  EELKSLFNTvAVLcCVHQ
Mutations I/V W/C
Epitope Location I10V W14C
HXB2 Location I82V W86C
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other
Note Subject 3 had I82V, W86C, variations in 14/15 sequences at 1 year, within and downstream of the putative epitope LFNTVAVL.


Variant ID.  3880
Epitope Seq.  EELKSLFNTIAVLWCVHQ
Variant Seq.  EELKpLFNTvAVLcCVHQ
Mutations I/V W/C S/P
Epitope Location I10V W14C S5P
HXB2 Location I82V W86C S77P
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other
Note Subject 3 had S77P, I82V, W86C, variations in 1/15 sequences at 1 year, within, upstream, and downstream of the putative epitope LFNTVAVL.

References

Jiang2016 Xifeng Jiang, Qiyan Jia, Lu Lu, Fei Yu, Jishen Zheng, Weiguo Shi, Lifeng Cai, Shibo Jiang, and Keliang Liu. A Novel Bispecific Peptide HIV-1 Fusion Inhibitor Targeting the N-Terminal Heptad Repeat and Fusion Peptide Domains in gp41. Amino Acids, 48(12):2867-2873, Dec 2016. PubMed ID: 27631437. Show all entries for this paper.


Displaying record number 61462

HXB2 Location  Gag(92-101)   Gag Epitope Map
View variants at this location
Epitope IEVKDTKEAL   Epitope Alignment
Variants
IEVKDTrEAL   observed variant
IgVKDTKEAL   observed variant
IEiKDTKEAL   observed variant
IEVKDTKEAv   observed variant
{HQr}IEVKDTKEAv{DKLEE}   observed variant
{HQr}IgVKDTKEAL{DKLEE}   observed variant
{HQr}IaVKDTKEAL{DKLEE}   observed variant
{HQr}IEVKDTKEAL{DKLEE}   observed variant
Epitope Name IL10-B40
Species (MHC/HLA human

Variant Details

Showing all: 8 variant(s).


Variant ID.  3888
Epitope Seq.  IEVKDTKEAL
Variant Seq.  IEVKDTrEAL
Mutations K/R
Epitope Location K7R
HXB2 Location K98R
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 2/10 HIV-1 sequences in Subject 12 carried an K98R variation within epitope IL10 at 3 months post-infection, IEVKDTrEAL, with no flanking mutations.


Variant ID.  3889
Epitope Seq.  IEVKDTKEAL
Variant Seq.  IgVKDTKEAL
Mutations E/G
Epitope Location E2G
HXB2 Location E93G
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 1/12 HIV-1 sequences in Subject 12 carried an E93G variation within epitope IL10 at 1 year post-infection, IgVKDTKEAL, with no flanking mutations.


Variant ID.  3890
Epitope Seq.  IEVKDTKEAL
Variant Seq.  IEiKDTKEAL
Mutations V/I
Epitope Location V3I
HXB2 Location V94I
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 1/12 HIV-1 sequences in Subject 12 carried an V94I variation within epitope IL10 at 1 year post-infection, IEiKDTKEAL, with no flanking mutations.


Variant ID.  3891
Epitope Seq.  IEVKDTKEAL
Variant Seq.  IEVKDTKEAv
Mutations L/V
Epitope Location L10V
HXB2 Location L101V
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 1/12 HIV-1 sequences in Subject 12 carried an L101V variation within epitope IL10 at 1 year post-infection, IEVKDTKEAv, with no flanking mutations.


Variant ID.  3892
Epitope Seq.  {HQK}IEVKDTKEAL{DKLEE}
Variant Seq.  {HQr}IEVKDTKEAv{DKLEE}
Mutations L/V K/R
Epitope Location L+1V K-1R
HXB2 Location L102V K91R
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 3/12 HIV-1 sequences in Subject 12 carried K91R, L101V variations within epitope IL10 at 1 year post-infection, IEVKDTKEAv, with the upstream flanking mutation at -1 position.


Variant ID.  3893
Epitope Seq.  {HQK}IEVKDTKEAL{DKLEE}
Variant Seq.  {HQr}IgVKDTKEAL{DKLEE}
Mutations K/R E/G
Epitope Location K-1R E2G
HXB2 Location K91R E93G
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 2/12 HIV-1 sequences in Subject 12 carried K91R, E93G variations within epitope IL10 at 1 year post-infection, IgVKDTKEAL, with the upstream flanking mutation at -1 position.


Variant ID.  3894
Epitope Seq.  {HQK}IEVKDTKEAL{DKLEE}
Variant Seq.  {HQr}IaVKDTKEAL{DKLEE}
Mutations K/R E/A
Epitope Location K-1R E2A
HXB2 Location K91R E93A
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 2/12 HIV-1 sequences in Subject 12 carried K91R, E93A variations within epitope IL10 at 1 year post-infection, IaVKDTKEAL, with the upstream flanking mutation at -1 position.


Variant ID.  3895
Epitope Seq.  {HQK}IEVKDTKEAL{DKLEE}
Variant Seq.  {HQr}IEVKDTKEAL{DKLEE}
Mutations K/R
Epitope Location K-1R
HXB2 Location K91R
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 1/10 HIV-1 sequences in Subject 12 carried a K91R variation flanking epitope IL10 at 3 months post-infection, with the upstream flanking mutation at -1 position.

References

Jiang2016 Xifeng Jiang, Qiyan Jia, Lu Lu, Fei Yu, Jishen Zheng, Weiguo Shi, Lifeng Cai, Shibo Jiang, and Keliang Liu. A Novel Bispecific Peptide HIV-1 Fusion Inhibitor Targeting the N-Terminal Heptad Repeat and Fusion Peptide Domains in gp41. Amino Acids, 48(12):2867-2873, Dec 2016. PubMed ID: 27631437. Show all entries for this paper.


Displaying record number 61460

HXB2 Location  Gag(210-218)   Gag Epitope Map
View variants at this location
Epitope AEWDRVHPV   Epitope Alignment
Variants
{A}tEWDRVHPV{HAGPIPPG}   observed variant
{A}AdWDRVHPV{HAGPIPPG}   observed variant
{A}AdWDRgHPV{HAGPIPPG}   observed variant
{A}AdWDRgHPV{HAGPIPlG}   observed variant
{A}vEWDRaHPi{HAGPIPPG}   observed variant
Epitope Name AV9-B40
Species (MHC/HLA human

Variant Details

Showing all: 5 variant(s).


Variant ID.  3881
Epitope Seq.  {A}AEWDRVHPV{HAGPIPPG}
Variant Seq.  {A}tEWDRVHPV{HAGPIPPG}
Mutations A/T
Epitope Location A1T
HXB2 Location A210T
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Sequence
Note 1/17 HIV-1 sequences in Subject 4 carried an A210T variation within epitope AV9 at 3 months but none did at 1 year post-infection.


Variant ID.  3882
Epitope Seq.  {A}AEWDRVHPV{HAGPIPPG}
Variant Seq.  {A}AdWDRVHPV{HAGPIPPG}
Mutations E/D
Epitope Location E2D
HXB2 Location E211D
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Sequence
Note 13/16 HIV-1 sequences in Subject 4 carried an E211D variation within epitope AV9 at 1 year post-infection, and 5/16 of those were single variants AdWDRVHPV.


Variant ID.  3883
Epitope Seq.  {A}AEWDRVHPV{HAGPIPPG}
Variant Seq.  {A}AdWDRgHPV{HAGPIPPG}
Mutations E/D V/G
Epitope Location E2D V6G
HXB2 Location E211D V215G
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Sequence
Note 8/16 HIV-1 sequences in Subject 4 carried an E211D, V215G variations within epitope AV9 at 1 year post-infection, and 7/16 of those were double variants AdWDRgHPV with no flanking mutations.


Variant ID.  3884
Epitope Seq.  {A}AEWDRVHPV{HAGPIPPG}
Variant Seq.  {A}AdWDRgHPV{HAGPIPlG}
Mutations E/D V/G P/L
Epitope Location E2D V6G P+9L
HXB2 Location E211D V215G P227L
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Sequence
Note 1/16 HIV-1 sequences in Subject 4 carried an E211D, V215G, P227L variation within and downstream of epitope AV9 at 1 year post-infection, AdWDRgHPV with a flanking mutation at +7 position.


Variant ID.  3885
Epitope Seq.  {A}AEWDRVHPV{HAGPIPPG}
Variant Seq.  {A}vEWDRaHPi{HAGPIPPG}
Mutations V/I A/V V/A
Epitope Location V+1I A1V V6A
HXB2 Location V219I A210V V215A
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Sequence
Note 3/16 HIV-1 sequences in Subject 4 carried A210V, V215A, V219I variations within epitope AV9 at 1 year post-infection, vEWDRaHPt with no flanking mutations.

References

Jiang2016 Xifeng Jiang, Qiyan Jia, Lu Lu, Fei Yu, Jishen Zheng, Weiguo Shi, Lifeng Cai, Shibo Jiang, and Keliang Liu. A Novel Bispecific Peptide HIV-1 Fusion Inhibitor Targeting the N-Terminal Heptad Repeat and Fusion Peptide Domains in gp41. Amino Acids, 48(12):2867-2873, Dec 2016. PubMed ID: 27631437. Show all entries for this paper.


Displaying record number 61461

HXB2 Location  Gag(226-236)   Gag Epitope Map
View variants at this location
Epitope GQMREPRGSDI   Epitope Alignment
Variants
{aDWDRVHPVHAGPIPP}GQMREPRGSDI   observed variant
{aDWDRaHPVHAGPIPP}GQMREPRGSDI   observed variant
Epitope Name GI11-B13
Species (MHC/HLA human

Variant Details

Showing all: 2 variant(s).


Variant ID.  3886
Epitope Seq.  {VDWDRVHPVHAGPIPP}GQMREPRGSDI
Variant Seq.  {aDWDRVHPVHAGPIPP}GQMREPRGSDI
Mutations V/A
Epitope Location V2A
HXB2 Location V227A
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 14/16 HIV-1 sequences in Subject 5 carried a -16 flanking variation upstream at V227A for epitope GI11 at 1 year post-infection.


Variant ID.  3887
Epitope Seq.  {VDWDRVHPVHAGPIPP}GQMREPRGSDI
Variant Seq.  {aDWDRaHPVHAGPIPP}GQMREPRGSDI
Mutations V/A V/A
Epitope Location V2A V7A
HXB2 Location V227A V232A
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 2/16 HIV-1 sequences in Subject 5 carried -11, -16 flanking variations downstream at V227A, V232A for epitope GI11 at 1 year post-infection.

References

Jiang2016 Xifeng Jiang, Qiyan Jia, Lu Lu, Fei Yu, Jishen Zheng, Weiguo Shi, Lifeng Cai, Shibo Jiang, and Keliang Liu. A Novel Bispecific Peptide HIV-1 Fusion Inhibitor Targeting the N-Terminal Heptad Repeat and Fusion Peptide Domains in gp41. Amino Acids, 48(12):2867-2873, Dec 2016. PubMed ID: 27631437. Show all entries for this paper.


Displaying record number 61457

HXB2 Location  Gag(263-272)   Gag Epitope Map
View variants at this location
Epitope KRWIILGLNK   Epitope Alignment
Variants
{PaGDIY}KRWIILGLNK   observed variant
Epitope Name KK10-B27
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  3874
Epitope Seq.  {PVGDIY}KRWIILGLNK
Variant Seq.  {PaGDIY}KRWIILGLNK
Mutations V/A
Epitope Location V-5A
HXB2 Location V258A
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 1/16 HIV-1 sequences in Subject 2 carried a flanking variation for epitope KK10 at 3 months but none did at 1 year post-infection.

References

Jiang2016 Xifeng Jiang, Qiyan Jia, Lu Lu, Fei Yu, Jishen Zheng, Weiguo Shi, Lifeng Cai, Shibo Jiang, and Keliang Liu. A Novel Bispecific Peptide HIV-1 Fusion Inhibitor Targeting the N-Terminal Heptad Repeat and Fusion Peptide Domains in gp41. Amino Acids, 48(12):2867-2873, Dec 2016. PubMed ID: 27631437. Show all entries for this paper.


Displaying record number 61458

HXB2 Location  Gag(353-370)   Gag Epitope Map
View variants at this location
Epitope VGGPSHKARVLAEAMSQA   Epitope Alignment
Variants
VGGPgHKARVLAEAMSQA   observed variant
VGGPgHKARVLAEAMSQv   observed variant
Epitope Name OLP-45
Species (MHC/HLA human

Variant Details

Showing all: 2 variant(s).


Variant ID.  3875
Epitope Seq.  VGGPSHKARVLAEAMSQA
Variant Seq.  VGGPgHKARVLAEAMSQA
Mutations S/G
Epitope Location S5G
HXB2 Location S357G
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note Subject 1 had an S357G variation in 11/16 and 8/16 sequences at 3 months and 1 year respectively, within the putative epitope GPgHKARVL.


Variant ID.  3876
Epitope Seq.  VGGPSHKARVLAEAMSQA
Variant Seq.  VGGPgHKARVLAEAMSQv
Mutations A/V S/G
Epitope Location A18V S5G
HXB2 Location A370V S357G
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note Subject 1 had S357G, A370V variations in 8/16 sequences at 1 year, within and downstream of the putative epitope GPgHKARVL.

References

Jiang2016 Xifeng Jiang, Qiyan Jia, Lu Lu, Fei Yu, Jishen Zheng, Weiguo Shi, Lifeng Cai, Shibo Jiang, and Keliang Liu. A Novel Bispecific Peptide HIV-1 Fusion Inhibitor Targeting the N-Terminal Heptad Repeat and Fusion Peptide Domains in gp41. Amino Acids, 48(12):2867-2873, Dec 2016. PubMed ID: 27631437. Show all entries for this paper.


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