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Found 3 matching records:

Displaying record number 53742

HXB2 Location Gag(77-85) Gag Epitope Map
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SLYNTVATL

`SLfNTVATL`		observed variant
`SLYNTiATL`		observed variant

Species (MHC/HLA) human(A2)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`500`
Epitope Seq.	`SLYNTVATL`
Variant Seq.	`SLfNTVATL`
Mutations	Y/F
Epitope Location	Y3F
HXB2 Location	Y79F
Mutation Type	OV: observed variant
Note	Two of the subjects carried this variant of the epitope

Variant ID.	`501`
Epitope Seq.	`SLYNTVATL`
Variant Seq.	`SLYNTiATL`
Mutations	V/I
Epitope Location	V6I
HXB2 Location	V82I
Mutation Type	OV: observed variant
Note	One of the subjects carried this variant of the epitope.

References

Jansen2005a Christine A. Jansen, Stefan Kostense, Kristin Vandenberghe, Nening M. Nanlohy, Iris M. De Cuyper, Erwan Piriou, Erik H. Manting, Frank Miedema, and Debbie van Baarle. High Responsiveness of HLA-B57-Restricted Gag-Specific CD8+ T Cells In Vitro May Contribute to the Protective Effect of HLA-B57 in HIV-Infection. Eur. J. Immunol., 35(1):150-158, Jan 2005. PubMed ID: 15593302. Show all entries for this paper.

Displaying record number 53741

HXB2 Location Gag(162-172) Gag Epitope Map
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Epitope

KAFSPEVIPMF

Epitope Alignment

Variants

`KvFSPEVIPMF`		observed variant
`eAFSPEVIPMF`		observed variant
`KtFSPEVIPMF`		observed variant

Epitope Name KAF

Species (MHC/HLA) human(B57)

Variant Details

Showing all: 3 variant(s).

Variant ID.	`502`
Epitope Seq.	`KAFSPEVIPMF`
Variant Seq.	`KvFSPEVIPMF`
Mutations	A/V
Epitope Location	A2V
HXB2 Location	A163V
Mutation Type	OV: observed variant
Note	Variant was found in 2/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs.

Variant ID.	`503`
Epitope Seq.	`KAFSPEVIPMF`
Variant Seq.	`eAFSPEVIPMF`
Mutations	K/E
Epitope Location	K1E
HXB2 Location	K162E
Mutation Type	OV: observed variant
Note	Variant was found in 1/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs.

Variant ID.	`504`
Epitope Seq.	`KAFSPEVIPMF`
Variant Seq.	`KtFSPEVIPMF`
Mutations	A/T
Epitope Location	A2T
HXB2 Location	A163T
Mutation Type	OV: observed variant
Note	Variant was found in 1/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs.

References

Displaying record number 53743

HXB2 Location Gag(260-267) Gag Epitope Map
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Epitope

EIYRKWII

Epitope Alignment

Variants

`EfYRKWII`		observed variant
`rIYRKWII`		observed variant

Species (MHC/HLA) human(B8)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`505`
Epitope Seq.	`EIYRKWII`
Variant Seq.	`EfYRKWII`
Mutations	I/F
Epitope Location	I2F
HXB2 Location	I261F
Mutation Type	OV: observed variant
Note	Variant was found in 1/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs.

Variant ID.	`506`
Epitope Seq.	`EIYRKWII`
Variant Seq.	`rIYRKWII`
Mutations	E/R
Epitope Location	E1R
HXB2 Location	E260R
Mutation Type	OV: observed variant
Note	Variant was found in 1/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs.