Found 1 matching record:
HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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Epitope |
SLYNTVATL
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Epitope Alignment | ||||||||||
Variants |
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Epitope Name | SL9 | |||||||||||
Species (MHC/HLA) | human(A*02:01) |
Showing all: 3 variant(s).
Variant ID. | 2340 |
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Epitope Seq. | SLYNTVATL |
Variant Seq. | SLYNTiAvL |
Mutations | V/I T/V |
Epitope Location | V6I T8V |
HXB2 Location | V82I T84V |
Mutation Type | LE: literature escape |
Epitope Subtype | B |
Variant Subtype | B |
Method | CD8 T-cell Elispot - IFNy, Chromium-release assay |
Note | SL9 variant V82I/T84V, SLYNTiAvL, was recognized by different TCR mutants with differing functional avidities. |
Variant ID. | 2341 |
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Epitope Seq. | SLYNTVATL |
Variant Seq. | SLfNTVATL |
Mutations | Y/F |
Epitope Location | Y3F |
HXB2 Location | Y79F |
Mutation Type | LE: literature escape |
Epitope Subtype | B |
Variant Subtype | B |
Method | CD8 T-cell Elispot - IFNy, Chromium-release assay |
Note | SL9 variant Y79F, SLfNTVATL, was recognized by different TCR mutants with differing functional avidities. |
Variant ID. | 2342 |
---|---|
Epitope Seq. | SLYNTVATL |
Variant Seq. | SLYNTiATL |
Mutations | V/I |
Epitope Location | V6I |
HXB2 Location | V82I |
Mutation Type | LE: literature escape |
Epitope Subtype | B |
Variant Subtype | B |
Method | CD8 T-cell Elispot - IFNy, Chromium-release assay |
Note | SL9 variant V82I, SLYNTiATL, was recognized by different TCR mutants with differing functional avidities. |
Bennett2010 Michael S. Bennett, Aviva Joseph, Hwee L. Ng, Harris Goldstein, and Otto O. Yang. Fine-Tuning of T-Cell Receptor Avidity to Increase HIV Epitope Variant Recognition by Cytotoxic T Lymphocytes. AIDS, 24(17):2619-2628, 13 Nov 2010. PubMed ID: 20881472. Show all entries for this paper.
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