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Found 1 matching record:

Displaying record number 62254

HXB2 Location  Gag(18-26)   Gag Epitope Map
View variants at this location
Epitope KIRLRPGGK   Epitope Alignment
Variants
KIRLRPGGn   susceptible form
KIRLRPeGK   susceptible form
KIkLRPGGK   susceptible form
KIqLRPGGK   susceptible form
KIkLRPGGr   susceptible form
Species (MHC/HLA human(A*03)

Variant Details

Showing all: 5 variant(s).


Variant ID.  4369
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIRLRPGGn
Mutations K/N
Epitope Location K9N
HXB2 Location K26N
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KIRLRPGGn was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4370
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIRLRPeGK
Mutations G/E
Epitope Location G7E
HXB2 Location G24E
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KIRLRPeGk was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4371
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIkLRPGGK
Mutations R/K
Epitope Location R3K
HXB2 Location R20K
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KIkLRPGGK was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4372
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIqLRPGGK
Mutations R/Q
Epitope Location R3Q
HXB2 Location R20Q
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KIqLRPGGK was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4373
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIkLRPGGr
Mutations R/K K/R
Epitope Location R3K K9R
HXB2 Location R20K K26R
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KIkLRPGGr was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

References

Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.


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