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Displaying record number 62254

HXB2 Location Gag(18-26) Gag Epitope Map
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KIRLRPGGK

`KIRLRPGGn`		susceptible form
`KIRLRPeGK`		susceptible form
`KIkLRPGGK`		susceptible form
`KIqLRPGGK`		susceptible form
`KIkLRPGGr`		susceptible form

Species (MHC/HLA) human(A*03)

Variant Details

Showing all: 5 variant(s).

Variant ID.	`4369`
Epitope Seq.	`KIRLRPGGK`
Variant Seq.	`KIRLRPGGn`
Mutations	K/N
Epitope Location	K9N
HXB2 Location	K26N
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KIRLRPGGn was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4370`
Epitope Seq.	`KIRLRPGGK`
Variant Seq.	`KIRLRPeGK`
Mutations	G/E
Epitope Location	G7E
HXB2 Location	G24E
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KIRLRPeGk was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4371`
Epitope Seq.	`KIRLRPGGK`
Variant Seq.	`KIkLRPGGK`
Mutations	R/K
Epitope Location	R3K
HXB2 Location	R20K
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KIkLRPGGK was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4372`
Epitope Seq.	`KIRLRPGGK`
Variant Seq.	`KIqLRPGGK`
Mutations	R/Q
Epitope Location	R3Q
HXB2 Location	R20Q
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KIqLRPGGK was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4373`
Epitope Seq.	`KIRLRPGGK`
Variant Seq.	`KIkLRPGGr`
Mutations	R/K K/R
Epitope Location	R3K K9R
HXB2 Location	R20K K26R
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KIkLRPGGr was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

References

Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.