HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 62010

HXB2 Location  Gag(162-172)   Gag Epitope Map
View variants at this location
Epitope KAFSPEVIPMF   Epitope Alignment
KAFSaEVIPMF   TCR related mutation
Epitope Name B*57-KF11
Species (MHC/HLA human(B*57)

Variant Details

Showing all: 1 variant(s).

Variant ID.  4200
Variant Seq.  KAFSaEVIPMF
Mutations P/A
Epitope Location P5A
HXB2 Location P166A
Mutation Type TCR: TCR related mutation
Epitope Subtype B
Variant Subtype B
Method Other
Note Residue P34 is known to make TCR contacts. Upon mutation to P34A, the epitope network score changes to 4.42.


Gaiha2019 Gaurav D. Gaiha, Elizabeth J. Rossin, Jonathan Urbach, Christian Landeros, David R. Collins, Chioma Nwonu, Itai Muzhingi, Melis N. Anahtar, Olivia M. Waring, Alicja Piechocka-Trocha, Michael Waring, Daniel P. Worrall, Musie S. Ghebremichael, Ruchi M. Newman, Karen A. Power, Todd M. Allen, James Chodosh, and Bruce D. Walker. Structural Topology Defines Protective CD8+ T Cell Epitopes in the HIV Proteome. Science, 364(6439):480-484, 3 May 2019. PubMed ID: 31048489. Show all entries for this paper.

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