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Displaying record number 61675

HXB2 Location  Gag(161-172)   Gag Epitope Map
View variants at this location
Epitope EKAFSPEVIPMF   Epitope Alignment
Variants
dKAFSPEVIPMF   HLA association
EKsFSPEVIPMF   HLA association
EKAFnPEVIPMF   HLA association
EKgFSPEVIPMF   HLA association
EKAFkPEVIPMF   HLA association
Epitope Name Gag-KF11
Species (MHC/HLA human(B*57:03, B*58:01)

Variant Details

Showing all: 5 variant(s).


Variant ID.  4060
Epitope Seq.  EKAFSPEVIPMF
Variant Seq.  dKAFSPEVIPMF
Mutations E/D
Epitope Location E1D
HXB2 Location E161D
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Computer prediction
Note HLA-associated escape, dKAFSPEVIPMF, was associated more strongly with HLA-B*5703 than with HLA-B*5801.


Variant ID.  4061
Epitope Seq.  EKAFSPEVIPMF
Variant Seq.  EKsFSPEVIPMF
Mutations A/S
Epitope Location A3S
HXB2 Location A163S
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Computer prediction
Note HLA-associated escape, EKsFSPEVIPMF, was associated more strongly with HLA-B*5703 than with HLA-B*5801.


Variant ID.  4062
Epitope Seq.  EKAFSPEVIPMF
Variant Seq.  EKAFnPEVIPMF
Mutations S/N
Epitope Location S5N
HXB2 Location S165N
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Computer prediction
Note HLA-associated escape, EKAFnPEVIPMF, was associated more strongly with HLA-B*5703 than with HLAs-B*5801 and B*5702.


Variant ID.  4063
Epitope Seq.  EKAFSPEVIPMF
Variant Seq.  EKgFSPEVIPMF
Mutations A/G
Epitope Location A3G
HXB2 Location A163G
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Computer prediction
Note HLA-associated escape, EKgFSPEVIPMF, was associated more strongly with HLA-B*5703 than with HLAs-B*5801 and B*5702.


Variant ID.  4064
Epitope Seq.  EKAFSPEVIPMF
Variant Seq.  EKAFkPEVIPMF
Mutations S/K
Epitope Location S5K
HXB2 Location S165K
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Computer prediction
Note HLA-associated escape, EKAFkPEVIPMF, was associated most strongly with HLA-B*5703.

References

Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.


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