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Found 1 matching record:

Displaying record number 61674

HXB2 Location  Gag(146-155)   Gag Epitope Map
View variants at this location
Epitope AISPRTLNAW   Epitope Alignment
Variants
pISPRTLNAW   HLA association
AlSPRTLNAW   HLA association
AmSPRTLNAW   HLA association
Epitope Name Gag-IW9
Species (MHC/HLA human(B*57:02, B*57:03, B*58:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  4057
Epitope Seq.  AISPRTLNAW
Variant Seq.  pISPRTLNAW
Mutations A/P
Epitope Location A1P
HXB2 Location A146P
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, pISPRTLNAW, was associated more strongly with HLAs-B*5702 and B*5703 than with HLA-B*5801.


Variant ID.  4058
Epitope Seq.  AISPRTLNAW
Variant Seq.  AlSPRTLNAW
Mutations I/L
Epitope Location I2L
HXB2 Location I147L
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, AlSPRTLNAW, was associated more strongly with HLAs-B*5702 and B*5703 than with HLA-B*5801.


Variant ID.  4059
Epitope Seq.  AISPRTLNAW
Variant Seq.  AmSPRTLNAW
Mutations I/M
Epitope Location I2M
HXB2 Location I147M
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, AmSPRTLNAW, was associated more strongly with HLA-B*5703 than with HLA-B*5801.

References

Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.


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