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Displaying record number 61615

HXB2 Location Gag(71-79) Gag Epitope Map
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GSEELRSLY

`GSEELkSLY`
`GSEELRSLf`

Epitope Name Gag A01-GY9

Species (MHC/HLA) human(A*01)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`4001`
Epitope Seq.	`GSEELRSLY`
Variant Seq.	`GSEELkSLY`
Mutations	R/K
Epitope Location	R6K
HXB2 Location	R76K
Mutation Type
Epitope Subtype	B
Variant Subtype	B
Method	Other, Sequence
Note	30.8% of the sequences on d165 were this haplotype variant, GSEELkSLY, disappearing at later time points.

Variant ID.	`4002`
Epitope Seq.	`GSEELRSLY`
Variant Seq.	`GSEELRSLf`
Mutations	Y/F
Epitope Location	Y9F
HXB2 Location	Y79F
Mutation Type
Epitope Subtype	B
Variant Subtype	B
Method	Other, Sequence
Note	62.2% of the sequences on d1543, the last time point tested, were this haplotype variant, GSEELRSLf.

References

Henn2012 Matthew R. Henn, Christian L. Boutwell, Patrick Charlebois, Niall J. Lennon, Karen A. Power, Alexander R. Macalalad, Aaron M. Berlin, Christine M. Malboeuf, Elizabeth M. Ryan, Sante Gnerre, Michael C. Zody, Rachel L. Erlich, Lisa M. Green, Andrew Berical, Yaoyu Wang, Monica Casali, Hendrik Streeck, Allyson K. Bloom, Tim Dudek, Damien Tully, Ruchi Newman, Karen L. Axten, Adrianne D. Gladden, Laura Battis, Michael Kemper, Qiandong Zeng, Terrance P. Shea, Sharvari Gujja, Carmen Zedlack, Olivier Gasser, Christian Brander, Christoph Hess, Huldrych F. Günthard, Zabrina L. Brumme, Chanson J. Brumme, Suzane Bazner, Jenna Rychert, Jake P. Tinsley, Ken H. Mayer, Eric Rosenberg, Florencia Pereyra, Joshua Z. Levin, Sarah K. Young, Heiko Jessen, Marcus Altfeld, Bruce W. Birren, Bruce D. Walker, and Todd M. Allen. Whole Genome Deep Sequencing of HIV-1 Reveals the Impact of Early Minor Variants Upon Immune Recognition During Acute Infection. PLoS Pathog., 8(3):e1002529, 2012. PubMed ID: 22412369. Show all entries for this paper.