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Found 1 matching record:

Displaying record number 61537

HXB2 Location  Gag(211-221)   Gag Epitope Map
View variants at this location
Epitope EWDRVHPVHAG   Epitope Alignment
Variants
EWDRlHPVHAG   subtype-specific susceptible form
Epitope Name Gag p24 EG11-5V
Species (MHC/HLA human(B*40:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3939
Epitope Seq.  EWDRVHPVHAG
Variant Seq.  EWDRlHPVHAG
Mutations V/L
Epitope Location V5L
HXB2 Location V215L
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype CRF01_AE
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Intracellular cytokine staining, Sequence
Note B clade epitope EWDRlHPVHAG was found in 1/26 A/E patients of the KI cohort, though it was found in 921/1644 B virus and 48/315 clade A/E virus sequences in the Los Alamos HIV-1 database. It was recognized by CTL from clade A/E-infected patient KI-388 which had been elicited by consensus clade B EG11.

References

Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.


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