HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 61536

HXB2 Location  Gag(211-221)   Gag Epitope Map
View variants at this location
Epitope EWDRLHPVHAG   Epitope Alignment
Variants
EWDRvHPVHAG   subtype-specific susceptible form
Epitope Name Gag p24 EG11
Species (MHC/HLA human(B*40:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3938
Epitope Seq.  EWDRLHPVHAG
Variant Seq.  EWDRvHPVHAG
Mutations L/V
Epitope Location L5V
HXB2 Location L215V
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype CRF01_AE
Method CD8 T-cell Elispot - IFNy, Intracellular cytokine staining, Sequence
Note A/E clade epitope EWDRvHPVHAG was found in 5/26 A/E patients of the KI cohort, though it was found in 107/1644 B virus and 149/315 clade A/E virus sequences in the Los Alamos HIV-1 database. It was recognized by CTL from clade A/E-infected patient KI-388 which had been elicited by consensus clade B EG11.

References

Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health