HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 61462

HXB2 Location  Gag(92-101)   Gag Epitope Map
View variants at this location
Epitope IEVKDTKEAL   Epitope Alignment
Variants
IEVKDTrEAL   observed variant
IgVKDTKEAL   observed variant
IEiKDTKEAL   observed variant
IEVKDTKEAv   observed variant
{HQr}IEVKDTKEAv{DKLEE}   observed variant
{HQr}IgVKDTKEAL{DKLEE}   observed variant
{HQr}IaVKDTKEAL{DKLEE}   observed variant
{HQr}IEVKDTKEAL{DKLEE}   observed variant
Epitope Name IL10-B40
Species (MHC/HLA human

Variant Details

Showing all: 8 variant(s).


Variant ID.  3888
Epitope Seq.  IEVKDTKEAL
Variant Seq.  IEVKDTrEAL
Mutations K/R
Epitope Location K7R
HXB2 Location K98R
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 2/10 HIV-1 sequences in Subject 12 carried an K98R variation within epitope IL10 at 3 months post-infection, IEVKDTrEAL, with no flanking mutations.


Variant ID.  3889
Epitope Seq.  IEVKDTKEAL
Variant Seq.  IgVKDTKEAL
Mutations E/G
Epitope Location E2G
HXB2 Location E93G
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 1/12 HIV-1 sequences in Subject 12 carried an E93G variation within epitope IL10 at 1 year post-infection, IgVKDTKEAL, with no flanking mutations.


Variant ID.  3890
Epitope Seq.  IEVKDTKEAL
Variant Seq.  IEiKDTKEAL
Mutations V/I
Epitope Location V3I
HXB2 Location V94I
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 1/12 HIV-1 sequences in Subject 12 carried an V94I variation within epitope IL10 at 1 year post-infection, IEiKDTKEAL, with no flanking mutations.


Variant ID.  3891
Epitope Seq.  IEVKDTKEAL
Variant Seq.  IEVKDTKEAv
Mutations L/V
Epitope Location L10V
HXB2 Location L101V
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 1/12 HIV-1 sequences in Subject 12 carried an L101V variation within epitope IL10 at 1 year post-infection, IEVKDTKEAv, with no flanking mutations.


Variant ID.  3892
Epitope Seq.  {HQK}IEVKDTKEAL{DKLEE}
Variant Seq.  {HQr}IEVKDTKEAv{DKLEE}
Mutations L/V K/R
Epitope Location L+1V K-1R
HXB2 Location L102V K91R
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 3/12 HIV-1 sequences in Subject 12 carried K91R, L101V variations within epitope IL10 at 1 year post-infection, IEVKDTKEAv, with the upstream flanking mutation at -1 position.


Variant ID.  3893
Epitope Seq.  {HQK}IEVKDTKEAL{DKLEE}
Variant Seq.  {HQr}IgVKDTKEAL{DKLEE}
Mutations K/R E/G
Epitope Location K-1R E2G
HXB2 Location K91R E93G
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 2/12 HIV-1 sequences in Subject 12 carried K91R, E93G variations within epitope IL10 at 1 year post-infection, IgVKDTKEAL, with the upstream flanking mutation at -1 position.


Variant ID.  3894
Epitope Seq.  {HQK}IEVKDTKEAL{DKLEE}
Variant Seq.  {HQr}IaVKDTKEAL{DKLEE}
Mutations K/R E/A
Epitope Location K-1R E2A
HXB2 Location K91R E93A
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 2/12 HIV-1 sequences in Subject 12 carried K91R, E93A variations within epitope IL10 at 1 year post-infection, IaVKDTKEAL, with the upstream flanking mutation at -1 position.


Variant ID.  3895
Epitope Seq.  {HQK}IEVKDTKEAL{DKLEE}
Variant Seq.  {HQr}IEVKDTKEAL{DKLEE}
Mutations K/R
Epitope Location K-1R
HXB2 Location K91R
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Other, Sequence
Note 1/10 HIV-1 sequences in Subject 12 carried a K91R variation flanking epitope IL10 at 3 months post-infection, with the upstream flanking mutation at -1 position.

References

Jiang2016 Xifeng Jiang, Qiyan Jia, Lu Lu, Fei Yu, Jishen Zheng, Weiguo Shi, Lifeng Cai, Shibo Jiang, and Keliang Liu. A Novel Bispecific Peptide HIV-1 Fusion Inhibitor Targeting the N-Terminal Heptad Repeat and Fusion Peptide Domains in gp41. Amino Acids, 48(12):2867-2873, Dec 2016. PubMed ID: 27631437. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health