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Found 1 matching record:

Displaying record number 61460

HXB2 Location  Gag(210-218)   Gag Epitope Map
View variants at this location
Epitope AEWDRVHPV   Epitope Alignment
Variants
{A}tEWDRVHPV{HAGPIPPG}   observed variant
{A}AdWDRVHPV{HAGPIPPG}   observed variant
{A}AdWDRgHPV{HAGPIPPG}   observed variant
{A}AdWDRgHPV{HAGPIPlG}   observed variant
{A}vEWDRaHPi{HAGPIPPG}   observed variant
Epitope Name AV9-B40
Species (MHC/HLA human

Variant Details

Showing all: 5 variant(s).


Variant ID.  3881
Epitope Seq.  {A}AEWDRVHPV{HAGPIPPG}
Variant Seq.  {A}tEWDRVHPV{HAGPIPPG}
Mutations A/T
Epitope Location A1T
HXB2 Location A210T
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Sequence
Note 1/17 HIV-1 sequences in Subject 4 carried an A210T variation within epitope AV9 at 3 months but none did at 1 year post-infection.


Variant ID.  3882
Epitope Seq.  {A}AEWDRVHPV{HAGPIPPG}
Variant Seq.  {A}AdWDRVHPV{HAGPIPPG}
Mutations E/D
Epitope Location E2D
HXB2 Location E211D
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Sequence
Note 13/16 HIV-1 sequences in Subject 4 carried an E211D variation within epitope AV9 at 1 year post-infection, and 5/16 of those were single variants AdWDRVHPV.


Variant ID.  3883
Epitope Seq.  {A}AEWDRVHPV{HAGPIPPG}
Variant Seq.  {A}AdWDRgHPV{HAGPIPPG}
Mutations E/D V/G
Epitope Location E2D V6G
HXB2 Location E211D V215G
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Sequence
Note 8/16 HIV-1 sequences in Subject 4 carried an E211D, V215G variations within epitope AV9 at 1 year post-infection, and 7/16 of those were double variants AdWDRgHPV with no flanking mutations.


Variant ID.  3884
Epitope Seq.  {A}AEWDRVHPV{HAGPIPPG}
Variant Seq.  {A}AdWDRgHPV{HAGPIPlG}
Mutations E/D V/G P/L
Epitope Location E2D V6G P+9L
HXB2 Location E211D V215G P227L
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Sequence
Note 1/16 HIV-1 sequences in Subject 4 carried an E211D, V215G, P227L variation within and downstream of epitope AV9 at 1 year post-infection, AdWDRgHPV with a flanking mutation at +7 position.


Variant ID.  3885
Epitope Seq.  {A}AEWDRVHPV{HAGPIPPG}
Variant Seq.  {A}vEWDRaHPi{HAGPIPPG}
Mutations V/I A/V V/A
Epitope Location V+1I A1V V6A
HXB2 Location V219I A210V V215A
Mutation Type OV: observed variant
Epitope Subtype CRF01_AE
Variant Subtype CRF01_AE
Method Sequence
Note 3/16 HIV-1 sequences in Subject 4 carried A210V, V215A, V219I variations within epitope AV9 at 1 year post-infection, vEWDRaHPt with no flanking mutations.

References

Jiang2016 Xifeng Jiang, Qiyan Jia, Lu Lu, Fei Yu, Jishen Zheng, Weiguo Shi, Lifeng Cai, Shibo Jiang, and Keliang Liu. A Novel Bispecific Peptide HIV-1 Fusion Inhibitor Targeting the N-Terminal Heptad Repeat and Fusion Peptide Domains in gp41. Amino Acids, 48(12):2867-2873, Dec 2016. PubMed ID: 27631437. Show all entries for this paper.


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