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Found 1 matching record:

Displaying record number 61246

HXB2 Location  Gag(180-188)   Gag Epitope Map
View variants at this location
Epitope TPQDLNMML   Epitope Alignment
Variants
iPQDLNMML   HLA association; observed variant
iPhDLNMML   HLA association; observed variant
TPsDLNMML   HLA association; observed variant
TPhDLNMML   HLA association; observed variant
TPQDLNvML   HLA association; observed variant
TPgDLNMML   HLA association; observed variant
TPQDLNtML   HLA association; observed variant
Epitope Name TL9M7
Species (MHC/HLA human(B*42:01, B*81:01)

Variant Details

Showing all: 7 variant(s).


Variant ID.  3760
Epitope Seq.  TPQDLNMML
Variant Seq.  iPQDLNMML
Mutations T/I
Epitope Location T1I
HXB2 Location T180I
Mutation Type A: HLA association
OV: observed variant
Epitope Subtype A, CRF01_AE, CRF02_AG
Variant Subtype A, CRF01_AE, CRF02_AG
Method Other
Note Variant, iPQDLNMML, is present in 8.3% of B*42+ subjects; 5% of B*42-/B*81- subjects.


Variant ID.  3761
Epitope Seq.  TPQDLNMML
Variant Seq.  iPhDLNMML
Mutations T/I Q/H
Epitope Location T1I Q3H
HXB2 Location T180I Q182H
Mutation Type A: HLA association
OV: observed variant
Epitope Subtype A, CRF01_AE, CRF02_AG
Variant Subtype A, CRF01_AE, CRF02_AG
Method Other
Note Variant, iPhDLNMML, is present in 2.5% of B*42-/B*81- subjects.


Variant ID.  3762
Epitope Seq.  TPQDLNMML
Variant Seq.  TPsDLNMML
Mutations Q/S
Epitope Location Q3S
HXB2 Location Q182S
Mutation Type A: HLA association
OV: observed variant
Epitope Subtype A, CRF01_AE, CRF02_AG
Variant Subtype A, CRF01_AE, CRF02_AG
Method Other
Note Variant, TPsDLNMML, is present in 8.3% of B*42+ subjects; 2.5% of B*42-/B*81- subjects.


Variant ID.  3763
Epitope Seq.  TPQDLNMML
Variant Seq.  TPhDLNMML
Mutations Q/H
Epitope Location Q3H
HXB2 Location Q182H
Mutation Type A: HLA association
OV: observed variant
Epitope Subtype A, CRF01_AE, CRF02_AG
Variant Subtype A, CRF01_AE, CRF02_AG
Method Other
Note Variant, TPhDLNMML, is present in 2.5% of B*42-/B*81- subjects.


Variant ID.  3764
Epitope Seq.  TPQDLNMML
Variant Seq.  TPQDLNvML
Mutations M/V
Epitope Location M7V
HXB2 Location M186V
Mutation Type A: HLA association
OV: observed variant
Epitope Subtype A, CRF01_AE, CRF02_AG
Variant Subtype A, CRF01_AE, CRF02_AG
Method Other
Note Variant, TPQDLNvML, is present in 5% of B*42-/B*81- subjects.


Variant ID.  3765
Epitope Seq.  TPQDLNMML
Variant Seq.  TPgDLNMML
Mutations Q/G
Epitope Location Q3G
HXB2 Location Q182G
Mutation Type A: HLA association
OV: observed variant
Epitope Subtype A, CRF01_AE, CRF02_AG
Variant Subtype A, CRF01_AE, CRF02_AG
Method Other
Note Variant, TPgDLNMML, is present in 5% of B*42-/B*81- and 11.1% of the B*81+ subjects.


Variant ID.  3766
Epitope Seq.  TPQDLNMML
Variant Seq.  TPQDLNtML
Mutations M/T
Epitope Location M7T
HXB2 Location M186T
Mutation Type A: HLA association
OV: observed variant
Epitope Subtype A, CRF01_AE, CRF02_AG
Variant Subtype A, CRF01_AE, CRF02_AG
Method Other
Note Variant, TPQDLNtML, is present in 2.5% of B*42-/B*81- subjects and 16.7% of B*42+ subjects.

References

Geldmacher2009 Christof Geldmacher, Ian S. Metzler, Sodsai Tovanabutra, Tedi E. Asher, Emma Gostick, David R. Ambrozak, Constantinos Petrovas, Alexandra Schuetz, Njabulo Ngwenyama, Gustavo Kijak, Leonard Maboko, Michael Hoelscher, Francine McCutchan, David A. Price, Daniel C. Douek, and Richard A. Koup. Minor Viral and Host Genetic Polymorphisms Can Dramatically Impact the Biologic Outcome of an Epitope-Specific CD8 T-Cell Response. Blood, 114(8):1553-1562, 20 Aug 2009. PubMed ID: 19542300. Show all entries for this paper.


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