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Displaying record number 61204

HXB2 Location  Gag(22-30)   Gag Epitope Map
View variants at this location
Epitope RPGGKKHYM   Epitope Alignment
Variants
RPGGKKqYM   escape documented in this paper; replicative capacity reduced
RPGGKKsYM   escape documented in this paper; replicative capacity reduced
RPGGKKHYr   escape documented in this paper; replicative capacity reduced
RPGGKKHYk   escape documented in this paper; replicative capacity reduced
Epitope Name RM9
Species (MHC/HLA human(B*07:02, B*42:01)

Variant Details

Showing all: 4 variant(s).


Variant ID.  3710
Epitope Seq.  RPGGKKHYM
Variant Seq.  RPGGKKqYM
Mutations H/Q
Epitope Location H7Q
HXB2 Location H28Q
Mutation Type E: escape documented in this paper
RCR: replicative capacity reduced
Epitope Subtype B
Variant Subtype B
Method Other
Note RPGGKKqYM is an escape variant of RPGGKKHYM that reduces VRC.


Variant ID.  3711
Epitope Seq.  RPGGKKHYM
Variant Seq.  RPGGKKsYM
Mutations H/S
Epitope Location H7S
HXB2 Location H28S
Mutation Type E: escape documented in this paper
RCR: replicative capacity reduced
Epitope Subtype B
Variant Subtype B
Method Other
Note RPGGKKsYM is an escape variant of RPGGKKHYM that reduces VRC.


Variant ID.  3712
Epitope Seq.  RPGGKKHYM
Variant Seq.  RPGGKKHYr
Mutations M/R
Epitope Location M9R
HXB2 Location M30R
Mutation Type E: escape documented in this paper
RCR: replicative capacity reduced
Epitope Subtype B
Variant Subtype B
Method Other
Note RPGGKKHYr is an escape variant of RPGGKKHYM that reduces VRC.


Variant ID.  3713
Epitope Seq.  RPGGKKHYM
Variant Seq.  RPGGKKHYk
Mutations M/K
Epitope Location M9K
HXB2 Location M30K
Mutation Type E: escape documented in this paper
RCR: replicative capacity reduced
Epitope Subtype B
Variant Subtype B
Method Other
Note RPGGKKHYk is an escape variant of RPGGKKHYM that reduces VRC.

References

Kloverpris2015a Henrik N. Kløverpris, Alasdair Leslie, and Philip Goulder. Role of HLA Adaptation in HIV Evolution. Front. Immunol., 6:665, 18 Jan 2016. PubMed ID: 26834742. Show all entries for this paper.


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