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Found 1 matching record:

Displaying record number 61137

HXB2 Location  Gag(197-205)   Gag Epitope Map
View variants at this location
Epitope AMQMLKETI   Epitope Alignment
Variants
AMQMLKdTI   diminished response
Species (MHC/HLA human, mouse

Variant Details

Showing all: 1 variant(s).


Variant ID.  3574
Epitope Seq.  AMQMLKETI
Variant Seq.  AMQMLKdTI
Mutations E/D
Epitope Location E7D
HXB2 Location E203D
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy
Note AMQMLKdTI was a weaker variant of AMQMLKETI in Mosaic 1 of the tHIVconsvX vaccine, generation 2.

References

Ondondo2016 Beatrice Ondondo, Hayato Murakoshi, Genevieve Clutton, Sultan Abdul-Jawad, Edmund G.-T. Wee, Hiroyuki Gatanaga, Shinichi Oka, Andrew J. McMichael, Masafumi Takiguchi, Bette Korber, and Tomáš Hanke. Novel Conserved-region T-cell Mosaic Vaccine With High Global HIV-1 Coverage Is Recognized by Protective Responses in Untreated Infection. Mol. Ther., 24(4):832-842, Apr 2016. PubMed ID: 26743582. Show all entries for this paper.


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