HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(162-172) | Gag Epitope Map
View variants at this location |
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| Epitope |
KAFSPEVIPMF
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Epitope Alignment | |||||||||||||
| Variants |
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| Epitope Name | KF11 | ||||||||||||||
| Species (MHC/HLA) | human(B*57:01) | ||||||||||||||
Showing all: 4 variant(s).
| Variant ID. | 3344 |
|---|---|
| Epitope Seq. | KAFSPEVIPMF |
| Variant Seq. | KAFSPEVIPMs |
| Mutations | F/S |
| Epitope Location | F11S |
| HXB2 Location | F172S |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | HLA binding, Intracellular cytokine staining, Sequence |
| Note | Variant KAFSPEVIPMs was seen in 1/3 HRP subjects (patient P1). |
| Variant ID. | 3345 |
|---|---|
| Epitope Seq. | KAFSPEVIPMF |
| Variant Seq. | KAFSPEVIPMt |
| Mutations | F/T |
| Epitope Location | F11T |
| HXB2 Location | F172T |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | HLA binding, Intracellular cytokine staining, Sequence |
| Note | Variant KAFSPEVIPMt was seen in 1/3 HRP (patient P1) and 1/3 LRP (patient P6) subjects. |
| Variant ID. | 3346 |
|---|---|
| Epitope Seq. | KAFSPEVIPMF |
| Variant Seq. | KAFSPEiIPMF |
| Mutations | V/I |
| Epitope Location | V7I |
| HXB2 Location | V168I |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | HLA binding, Intracellular cytokine staining, Sequence |
| Note | Variant KAFSPEiIPMF was seen in 1/3 HRP (patient P1) and 1/3 LRP (patient P6) subjects. |
| Variant ID. | 3347 |
|---|---|
| Epitope Seq. | KAFSPEVIPMF |
| Variant Seq. | KAsSPEVIPMF |
| Mutations | F/S |
| Epitope Location | F3S |
| HXB2 Location | F164S |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | HLA binding, Intracellular cytokine staining, Sequence |
| Note | Variant KAsSPEVIPMF was seen in 1/3 LRP (patient P6) subjects. |
Buggert2014 Marcus Buggert, Melissa M. Norström, Marco Salemi, Frederick M. Hecht, and Annika C. Karlsson. Functional Avidity and IL-2/Perforin Production Is Linked to the Emergence of Mutations within HLA-B*5701-Restricted Epitopes and HIV-1 Disease Progression. J. Immunol., 192(10):4685-4696, 15 May 2014. PubMed ID: 24740510. Show all entries for this paper.