HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(147-158) | Gag Epitope Map
View variants at this location |
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| Epitope |
ISPRTLNAWVKV
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | CE1 | |||||
| Species (MHC/HLA) | mouse | |||||
Showing all: 1 variant(s).
| Variant ID. | 3207 |
|---|---|
| Epitope Seq. | ISPRTLNAWVKV |
| Variant Seq. | lSPRTLNAWVKV |
| Mutations | I/L |
| Epitope Location | I1L |
| HXB2 Location | I147L |
| Mutation Type | SSF: subtype-specific susceptible form |
| Epitope Subtype | B, C, M group |
| Variant Subtype | A |
| Method | Intracellular cytokine staining |
| Note | lSPRTLNAWVKV is the Clade-A variant of CE1. It was used in the p24CE2 vaccine form in this study, eliciting a strong T-helper response from the vaccinated mouse. |
Kulkarni2013 Viraj Kulkarni, Margherita Rosati, Antonio Valentin, Brunda Ganneru, Ashish K. Singh, Jian Yan, Morgane Rolland, Candido Alicea, Rachel Kelly Beach, Gen-Mu Zhang, Sylvie Le Gall, Kate E. Broderick, Niranjan Y. Sardesai, David Heckerman, Beatriz Mothe, Christian Brander, David B. Weiner, James I. Mullins, George N. Pavlakis, and Barbara K. Felber. HIV-1 p24(gag) Derived Conserved Element DNA Vaccine Increases the Breadth of Immune Response in Mice. PLoS One, 8(3):e60245, 2013. PubMed ID: 23555935. Show all entries for this paper.