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HIV Molecular Immunology Database

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Found 1 matching record:

Displaying record number 58746

HXB2 Location  Gag(17-31)   Gag Epitope Map
View variants at this location
Epitope EKIRLRPGGKKKYKL   Epitope Alignment
Variants
EKIRLRPGGKKKYqL   non-susceptible form; susceptible form
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  3135
Epitope Seq.  EKIRLRPGGKKKYKL
Variant Seq.  EKIRLRPGGKKKYqL
Mutations K/Q
Epitope Location K14Q
HXB2 Location K162Q
Mutation Type NSF: non-susceptible form
SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant EKIRLRPGGKKKYqL was detected in CP2 and ES2 HIV-1 sequences, but is only recognized by CTL from subject CP2.

References

Buckheit2012 Robert W. Buckheit, III, Tracy G. Allen, Angela Alme, Maria Salgado, Karen A. O'Connell, Sarah Huculak, Oluwaseun Falade-Nwulia, Thomas M. Williams, Joel E. Gallant, Robert F. Siliciano, and Joel N. Blankson. Host Factors Dictate Control of Viral Replication in Two HIV-1 Controller/Chronic Progressor Transmission Pairs. Nat Commun, 3:716, 2012. PubMed ID: 22395607. Show all entries for this paper.


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