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Found 1 matching record:

Displaying record number 58741

HXB2 Location  Gag(162-172)   Gag Epitope Map
View variants at this location
Epitope KAFSPEVIPMF   Epitope Alignment
Variants
KAFSPEVIPMF{t}   literature escape; non-susceptible form; susceptible form
Epitope Name KF11
Species (MHC/HLA human(B*57)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3130
Epitope Seq.  KAFSPEVIPMF{S}
Variant Seq.  KAFSPEVIPMF{t}
Mutations S/T
Epitope Location S+1T
HXB2 Location S173T
Mutation Type LE: literature escape
NSF: non-susceptible form
SF: susceptible form
Method CD4 T-cell Elispot - IFNy, Sequence
Note The S173T mutation to epitope KF11 is seen and recognized in HLA-B*57 individuals like ES38, but in this case was present in both ES38 as well as non-B*57-subject, CP2.

References

Buckheit2012 Robert W. Buckheit, III, Tracy G. Allen, Angela Alme, Maria Salgado, Karen A. O'Connell, Sarah Huculak, Oluwaseun Falade-Nwulia, Thomas M. Williams, Joel E. Gallant, Robert F. Siliciano, and Joel N. Blankson. Host Factors Dictate Control of Viral Replication in Two HIV-1 Controller/Chronic Progressor Transmission Pairs. Nat Commun, 3:716, 2012. PubMed ID: 22395607. Show all entries for this paper.


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