HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(162-172) | Gag Epitope Map
View variants at this location |
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| Epitope |
KAFSPEVIPMF
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | KF11 | |||||
| Species (MHC/HLA) | human(B*57) | |||||
Showing all: 1 variant(s).
| Variant ID. | 3130 |
|---|---|
| Epitope Seq. | KAFSPEVIPMF{S} |
| Variant Seq. | KAFSPEVIPMF{t} |
| Mutations | S/T |
| Epitope Location | S+1T |
| HXB2 Location | S173T |
| Mutation Type | LE: literature escape NSF: non-susceptible form SF: susceptible form |
| Method | CD4 T-cell Elispot - IFNy, Sequence |
| Note | The S173T mutation to epitope KF11 is seen and recognized in HLA-B*57 individuals like ES38, but in this case was present in both ES38 as well as non-B*57-subject, CP2. |
Buckheit2012 Robert W. Buckheit, III, Tracy G. Allen, Angela Alme, Maria Salgado, Karen A. O'Connell, Sarah Huculak, Oluwaseun Falade-Nwulia, Thomas M. Williams, Joel E. Gallant, Robert F. Siliciano, and Joel N. Blankson. Host Factors Dictate Control of Viral Replication in Two HIV-1 Controller/Chronic Progressor Transmission Pairs. Nat Commun, 3:716, 2012. PubMed ID: 22395607. Show all entries for this paper.