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Found 1 matching record:

Displaying record number 58684

HXB2 Location  Gag(162-172)   Gag Epitope Map
View variants at this location
Epitope KAFSPEVIPMF   Epitope Alignment
Variants
KxFSPEVIPMF   observed variant
KAFxPEVIPMF   observed variant
Epitope Name KF11
Species (MHC/HLA human(B*57:03)

Variant Details

Showing all: 2 variant(s).


Variant ID.  3100
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KxFSPEVIPMF
Mutations A/X
Epitope Location A2X
HXB2 Location A163X
Mutation Type OV: observed variant
Epitope Subtype C
Variant Subtype C
Method Sequence
Note Mutation KxFSPEVIPMF was seen in > 50% of HLA-B*5703-positive subjects.


Variant ID.  3101
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KAFxPEVIPMF
Mutations S/X
Epitope Location S4X
HXB2 Location S165X
Mutation Type OV: observed variant
Epitope Subtype C
Variant Subtype C
Method Sequence
Note Mutation KAFxPEVIPMF was seen in > 30% of HLA-B*5703-positive subjects.

References

Kloverpris2012 Henrik N. Kloverpris, Anette Stryhn, Mikkel Harndahl, Mary van der Stok, Rebecca P. Payne, Philippa C. Matthews, Fabian Chen, Lynn Riddell, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HLA-B*57 Micropolymorphism Shapes HLA Allele-Specific Epitope Immunogenicity, Selection Pressure, and HIV Immune Control. J. Virol., 86(2):919-929, Jan 2012. PubMed ID: 22090105. Show all entries for this paper.


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