HIV molecular immunology database
Found 1 matching record:
HXB2 Location | Gag(154-168) | Gag Epitope Map
View variants at this location |
||||
---|---|---|---|---|---|---|
Epitope |
AWVKVIEEKAFSPEV
|
Epitope Alignment | ||||
Variants |
|
|||||
Epitope Name | Peptide 38 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 2917 |
---|---|
Epitope Seq. | xAWVKVIEEKAFSPE |
Variant Seq. | nAWVKVvEEKAFSPE |
Mutations | x/N I/V |
Epitope Location | x1N I7V |
HXB2 Location | x154N I160V |
Mutation Type | SNSF: subtype-specific non-susceptible form |
Epitope Subtype | C |
Variant Subtype | B |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | Consensus Clade-B peptide 38, xAWVKVIEEKAFSPE, did not elicit a response from South African subjects carrying clade-C virus. |
Zembe2011 Lycias Zembe, Wendy A. Burgers, Heather B. Jaspan, Linda-Gail Bekker, Helba Bredell, Gwynneth Stevens, Jill Gilmour, Josephine H. Cox, Patricia Fast, Peter Hayes, Eftyhia Vardas, Carolyn Williamson, and Clive M. Gray. Intra- and Inter-Clade Cross-Reactivity by HIV-1 Gag Specific T-Cells Reveals Exclusive and Commonly Targeted Regions: Implications for Current Vaccine Trials. PLoS One, 6(10):e26096, 2011. PubMed ID: 22022524. Show all entries for this paper.