HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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| Epitope |
SLYNTVATL
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Epitope Alignment | ||||||||||||||||
| Variants |
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| Epitope Name | SL9 | |||||||||||||||||
| Species (MHC/HLA) | human(A*02) | |||||||||||||||||
Showing all: 5 variant(s).
| Variant ID. | 2705 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLYNTVAvL |
| Mutations | T/V |
| Epitope Location | T8V |
| HXB2 Location | T84V |
| Mutation Type | A: HLA association P: processing |
| Epitope Subtype | B |
| Variant Subtype | B |
| Note | A2-SL9 has known HLA-associated mutants (T8V, Y3F, V6I, V6I/T8V, Y3F/V6I). All 5 mutants displayed severely reduced half-lives. |
| Variant ID. | 2706 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLfNTVATL |
| Mutations | Y/F |
| Epitope Location | Y3F |
| HXB2 Location | Y79F |
| Mutation Type | A: HLA association P: processing |
| Epitope Subtype | B |
| Variant Subtype | B |
| Note | A2-SL9 has known HLA-associated mutants (T8V, Y3F, V6I, V6I/T8V, Y3F/V6I). All 5 mutants displayed severely reduced half-lives. |
| Variant ID. | 2707 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLYNTiATL |
| Mutations | V/I |
| Epitope Location | V6I |
| HXB2 Location | V82I |
| Mutation Type | A: HLA association P: processing |
| Epitope Subtype | B |
| Variant Subtype | B |
| Note | A2-SL9 has known HLA-associated mutants (T8V, Y3F, V6I, V6I/T8V, Y3F/V6I). All 5 mutants displayed severely reduced half-lives. |
| Variant ID. | 2708 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLYNTiAvL |
| Mutations | V/I T/V |
| Epitope Location | V6I T8V |
| HXB2 Location | V82I T84V |
| Mutation Type | A: HLA association P: processing |
| Epitope Subtype | B |
| Variant Subtype | B |
| Note | A2-SL9 has known HLA-associated mutants (T8V, Y3F, V6I, V6I/T8V, Y3F/V6I). All 5 mutants displayed severely reduced half-lives. |
| Variant ID. | 2709 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLfNTiATL |
| Mutations | Y/F V/I |
| Epitope Location | Y3F V6I |
| HXB2 Location | Y79F V82I |
| Mutation Type | A: HLA association P: processing |
| Epitope Subtype | B |
| Variant Subtype | B |
| Note | A2-SL9 has known HLA-associated mutants (T8V, Y3F, V6I, V6I/T8V, Y3F/V6I). All 5 mutants displayed severely reduced half-lives. |
Lazaro2011 Estibaliz Lazaro, Carl Kadie, Pamela Stamegna, Shao Chong Zhang, Pauline Gourdain, Nicole Y. Lai, Mei Zhang, Sergio A. Martinez, David Heckerman, and Sylvie Le Gall. Variable HIV Peptide Stability in Human Cytosol Is Critical to Epitope Presentation and Immune Escape. J. Clin. Invest., 121(6):2480-2492, Jun 2011. PubMed ID: 21555856. Show all entries for this paper.