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Found 1 matching record:

Displaying record number 57704

HXB2 Location  Gag(93-101)   Gag Epitope Map
View variants at this location
Epitope EIKDTKEAL   Epitope Alignment
Variants
EvKDTKEAL   susceptible form
dvKDTKEAL   susceptible form
Species (MHC/HLA human(B*08)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2598
Epitope Seq.  EIKDTKEAL
Variant Seq.  EvKDTKEAL
Mutations I/V
Epitope Location I2V
HXB2 Location I94V
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note Gag variant EvKDTKEAL was recognized by CTL 48 weeks into TI, in Patient 311.


Variant ID.  2599
Epitope Seq.  EIKDTKEAL
Variant Seq.  dvKDTKEAL
Mutations E/D I/V
Epitope Location E1D I2V
HXB2 Location E93D I94V
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note Gag variant dvKDTKEAL was recognized by CTL 48 weeks into TI, in Patient 311.

References

Schweighardt2010 Becky Schweighardt, Terri Wrin, Duncan A. Meiklejohn, Gerald Spotts, Christos J. Petropoulos, Douglas F. Nixon, and Frederick M. Hecht. Immune Escape Mutations Detected within HIV-1 Epitopes Associated with Viral Control During Treatment Interruption. J. Acquir. Immune Defic. Syndr., 53(1):36-46, Jan 2010. PubMed ID: 19910798. Show all entries for this paper.


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