HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 57701

HXB2 Location  Gag(28-36)   Gag Epitope Map
View variants at this location
Epitope KYKLKHIVW   Epitope Alignment
Variants
qYKLKHIVW   susceptible form
Species (MHC/HLA human(A*23)

Variant Details

Showing all: 1 variant(s).


Variant ID.  2595
Epitope Seq.  KYKLKHIVW
Variant Seq.  qYKLKHIVW
Mutations K/Q
Epitope Location K1Q
HXB2 Location K28Q
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note Gag variant qYKLKHIVW also elicited CTL response 48 weeks after start of TI in Patient 311.

References

Schweighardt2010 Becky Schweighardt, Terri Wrin, Duncan A. Meiklejohn, Gerald Spotts, Christos J. Petropoulos, Douglas F. Nixon, and Frederick M. Hecht. Immune Escape Mutations Detected within HIV-1 Epitopes Associated with Viral Control During Treatment Interruption. J. Acquir. Immune Defic. Syndr., 53(1):36-46, Jan 2010. PubMed ID: 19910798. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health