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Found 1 matching record:

Displaying record number 57700

HXB2 Location  Gag(21-35)   Gag Epitope Map
View variants at this location
Epitope LRPGGKKKYKLKHIV   Epitope Alignment
Variants
LRPGGKKqYKLKHIV   susceptible form
Species (MHC/HLA human(B*08)

Variant Details

Showing all: 1 variant(s).


Variant ID.  2594
Epitope Seq.  LRPGGKKKYKLKHIV
Variant Seq.  LRPGGKKqYKLKHIV
Mutations K/Q
Epitope Location K8Q
HXB2 Location K28Q
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note CTL response to variant LRPGGKKqYKLKHIV was also detected 48 weeks after TI began.

References

Schweighardt2010 Becky Schweighardt, Terri Wrin, Duncan A. Meiklejohn, Gerald Spotts, Christos J. Petropoulos, Douglas F. Nixon, and Frederick M. Hecht. Immune Escape Mutations Detected within HIV-1 Epitopes Associated with Viral Control During Treatment Interruption. J. Acquir. Immune Defic. Syndr., 53(1):36-46, Jan 2010. PubMed ID: 19910798. Show all entries for this paper.


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