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Found 1 matching record:

Displaying record number 56301

HXB2 Location  Gag(203-212)   Gag Epitope Map
View variants at this location
Epitope ETINEEAAEW   Epitope Alignment
Variants
ETINdEAAEW   susceptible form
Epitope Name EW10
Species (MHC/HLA human(A25)

Variant Details

Showing all: 1 variant(s).


Variant ID.  159
Epitope Seq.  ETINEEAAEW
Variant Seq.  ETINdEAAEW
Mutations E/D
Epitope Location E5D
HXB2 Location E207D
Mutation Type SF: susceptible form
Method Flow cytometric T-cell cytokine assay
Note ETINEEAAEW, elicited a response in 1 patient with low viremia who also targeted Nef epitopes with high frequency. Patient had both the index epitope and the variant ETINdEAAEW which was recognized.

References

Daucher2008 Marybeth Daucher, David A. Price, Jason M. Brenchley, Laurie Lamoreaux, Julia A. Metcalf, Catherine Rehm, Elizabeth Nies-Kraske, Elizabeth Urban, Christian Yoder, Diane Rock, Julie Gumkowski, Michael R. Betts, Mark R. Dybul, and Daniel C. Douek. Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells. J. Virol., 82(8):4102-4114, Apr 2008. PubMed ID: 18234797. Show all entries for this paper.


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