HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(74-82) | Gag Epitope Map
View variants at this location |
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| Epitope |
ELRSLYNTV
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Epitope Alignment | |||||||||||||
| Variants |
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| Species (MHC/HLA) | human(B8) | ||||||||||||||
Showing all: 4 variant(s).
| Variant ID. | 791 |
|---|---|
| Epitope Seq. | ELRSLYNTV |
| Variant Seq. | ELkSLYNTV |
| Mutations | R/K |
| Epitope Location | R3K |
| HXB2 Location | R76K |
| Mutation Type | OV: observed variant |
| Variant Subtype | B, CRF01_AE |
| Method | Sequence |
| Note | Patient was superinfected with three strains, B1, B2 and CRF01_AE. This was the infecting variant in CRF01_AE and it did not change over time. It was also the infecting variant in B1. |
| Variant ID. | 792 |
|---|---|
| Epitope Seq. | ELRSLYNTV |
| Variant Seq. | ELkSLYNTi |
| Mutations | R/K V/I |
| Epitope Location | R3K V9I |
| HXB2 Location | R76K V82I |
| Mutation Type | IE: inferred escape |
| Variant Subtype | B |
| Method | Sequence |
| Note | Patient was superinfected with three strains, B1, B2 and CRF01_AE. This variant developed in B1 to include 50% of the viruses within 4 years. |
| Variant ID. | 793 |
|---|---|
| Epitope Seq. | ELRSLYNTV |
| Variant Seq. | ELkSLfNTV |
| Mutations | R/K Y/F |
| Epitope Location | R3K Y6F |
| HXB2 Location | R76K Y79F |
| Mutation Type | OV: observed variant |
| Variant Subtype | B |
| Method | Sequence |
| Note | Patient was superinfected with three strains, B1, B2 and CRF01_AE. This was the infecting variant in B2. |
| Variant ID. | 2257 |
|---|---|
| Epitope Seq. | ELKSLFNTV |
| Variant Seq. | ELKSLyNTV |
| Mutations | F/Y |
| Epitope Location | F6Y |
| HXB2 Location | F79Y |
| Mutation Type | R: reversion |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | Sequence |
| Note | Patient was superinfected with three strains, B1, B2 and CRF01_AE. The B2 variant is epitope ELKSLFNTV and reversion variant ELKSLyNTV developed in B2 to include 67% of the viruses within 3 years. |
Kozaczynska2007 Karolina Kozaczynska, Marion Cornelissen, Peter Reiss, Fokla Zorgdrager, and Antoinette C. van der Kuyl. HIV-1 Sequence Evolution In Vivo after Superinfection with Three Viral Strains. Retrovirology, 4:59, 2007. PubMed ID: 17716368. Show all entries for this paper.