HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(17-34) | Gag Epitope Map
View variants at this location |
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| Epitope |
EKIRLRPGGKKKYRLKHL
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | GAG-03 | |||||
| Species (MHC/HLA) | human | |||||
Showing all: 1 variant(s).
| Variant ID. | 1957 |
|---|---|
| Epitope Seq. | EKIRLRPGGKKKYRLKHL |
| Variant Seq. | EKIRLRPGGKKhYmLKHL |
| Mutations | K/H R/M |
| Epitope Location | K12H R14M |
| HXB2 Location | K28H R30M |
| Mutation Type | SSF: subtype-specific susceptible form |
| Epitope Subtype | B |
| Variant Subtype | C |
| Method | CD8 T-cell Elispot - IFNy, Sequence |
| Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.